Cardinals (-3) over 49ERS
With weapons like Larry Fitzgerald (eight catches, 143 yards and one TD Sunday against theVikings) and Anquan Boldin (seven catches, 98 yards and two TDs) running wild, Kurt Warner's life is really not that complicated. Arizona has covered six of the last eight overall, with one push, and six of the last seven on the road. And since San Francisco has abandoned the running game (53 yards Sunday), the Cards will pound the one-dimensional Niners for an easy win.