New York Yankees (82-48) at Baltimore Orioles (54-77)
(L) Andy Pettitte (11-6) vs. (R) Jeremy Guthrie (9-12)
Take the Yankees with veteran left-hander Andy Pettitte (11-6, 4.18 ERA) on the hill. New York has won the last seven meetings versus Baltimore and Pettitte's last six starts against them. The right-hander is 25-6 with a 3.65 ERA in his career against the Orioles. Meanwhile, Baltimore has dropped five of its last 7 home games and counters with Jeremy Guthrie (9-12, 5.26). The right-hander is 2-0 with a 4.12 ERA in his last three starts, but 1-2 with a 5.21 ERA in three outings against the Yankees this year, 3-4 with a 4.82 ERA in nine career starts. The Orioles are 2-5 in Guthrie’s last 7 starts against the Yankees. New York is 7-2 in Pettitte's last 9 starts versus Orioles at Camden Yards.