Chicago sends Rich Harden (4-3, 4.53) to the mound. The right-hander 1-0 with a 3.43 ERA in four career starts versus Cleveland, but hasn't faced Cleveland since 2006. The Cubs are 8-3 in Hardens last 11 home starts. The Indians counter with Cliff Lee (4-6, 2.88 ERA), Cleveland is just 2-5 in the lefthander?s last 7 road starts, but Lee has pitched outstanding in interleague starts, going 12-2 with a 3.18 ERA in 20 interleague games.
Go with the Indians with Cliff Lee at the helm in his Wrigley Field debut. The southpaw has been lucrative to backers in interleague play.